What is atarax?


Detailed description:
Atarax is designated chemically like 1-(p-chlorobenzhydryl) 4-2-(2-hydroxyethoxy)-ethyl piperazine dihydrochloride.

Inert ingredients for the tablets are : acacia ; carnauba wax ; dibasic calcium phosphate ; gelatin ; lactose ; magnesium stearate ; precipitated calcium carbonate ; shellac ; sucrose ; talc ; white colored wax . The 10 mg tablets as well contain: sodium hydroxide; starch; titanium dioxide; Yellow 6 Lake. The 25 mg tablets as well contain: starch; velo darkened green. The 50 mg tablets as well contain: starch; velo yellow. The 100 mg tablets as well contain: alginic acid; Blue 1; polyethylene glycol; Red 3.
The inert components for the syrup are : alcohol ; menthol ; peppermint oil ; sodium benzoate ; spearmint oil ; sucrose ; water .


Atarax uses. Atarax is not related to chemically to the phenothiazines, reserpine, meprobamate, or even the benzodiazepines.

Atarax is not a cortical depressant; however its action might be because of a suppression of activity on certain vital regions of the subcortical part of the central nervous system. Main skeletal muscle relaxation has become demonstrated experimentally. Bronchodilator activity, and also anti- histaminic and analgesic effects had been demonstrated experimentally and proven clinically. An antiemetic effect, both by the apomorphine trial along with the veriloid test, had been demonstrated. Pharmacological and medical tests show that hydroxyzine in medical dosage would not increase gastric secretion or acidity in many cases has mild antisecretory activity. Hydroxyzine is quickly absorbed from the gastrointestinal system and Atarax’s medical effects are generally noted within 15 to thirty minutes after oral administration.

Atarax Side Effects

Side effects reported with the administration of Atarax (hydroxyzine hydrochloride) usually are moderate and temporary in nature.
Mouth dry.
Central Nervous System

Drowsiness is normally temporary and might go away in a couple of days of persisted treatment or even upon decrease of the dose. Involuntary motor activity which includes uncommon situations of tremor and convulsions had been reported, usually with doses substantially greater than those suggested. Clinically significant respiratory clinical-depression has not been reported at suggested doses.


Below is a small sample of reports in which side effects may be associated with Atarax. The details are not vetted and ought not to be regarded as confirmed clinical evidence.
Possible Atarax side effects in 54 year old female
Reported by a doctor from France on 2011-10-04
Patient: 54 year old female
Responses: Ocular High blood pressure
Suspect drug(s):
Possible Atarax side effects in 46 year old male
According to a doctor from France on 2011-10-08
Patient: 46 year old male
Responses: Eosinophil Count Increased, Toxic Skin Eruption
Unwanted occurrence resulted in: hospitalization
Suspect drug(s):
Administration route: Oral
Indication: Anxiety
Start date: 2011-08-30
End date: 2011-08-30
Sign: Musculoskeletal Pain
Start date: 2011-08-31
End date: 2011-08-31
Sign: Musculoskeletal Ache
Start date: 2011-08-31
End date: 2011-08-31
Possible Atarax side effects in 48 year old male

Reported by a physician (non-physician/pharmacist) from France on 2011-10-11
Patient: 48 year old man
Responses: OFF Label USE, Dyspnoea, Condition Aggravated, Leukocytosis, Rash Maculo-Papular, Myeloproliferative Problem, Toxic Skin Eruption
Undesirable event resulted in: hospitalization

Suspect drug(s):
Dosage: po
Administration route: Oral
Indication: Rash Maculo-Papular
Start date: 2011-08-09
End date: 2011-08-19

Dosage: po
Administration route: Oral
Sign: Rash Maculo-Papular
Begin date: 2011-08-09
Finish date: 2011-08-19

Atarax Dosage

For symptomatic pain relief of anxiety and tension related to psychoneurosis and as an adjunct in organic illness states through which anxiety is noticeable: in adults, 50–100 mg q .I .d. children under six years, 50 mg every day in separated doses and over six years, 50–100 mg every day in separated doses.

For use in the management of pruritus because of allergic problems for example chronic urticaria and atopic and also contact dermatoses, as well as in histamine-mediated pruritus: in adults, 25 mg t .I .d. Or q .I .d. ; children under six years , 50 mg every day in separated doses and over six years , 50–100 mg every day in separated doses .
As a sedative while utilized as a premedication and following basic anesthesia: 50–100 mg in adults and 0 .6 mg/kg in children.

While medication is begun by the intramuscular route of administration, subsequent doses might be administered orally.

As with all medicines, the dosage ought to be adjusted based on the patient’s reaction to treatment.


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