What is Crestor (rosuvastatin)?


CRESTOR is known as rosuvastatin calcium (the active ingredient). There is no generic form of Crestor available for consumers.
It is a lipid-lowering agent that belongs to a group of drugs known as “statins”, or HMG CoA reductase inhibitors. Crestor lowers the levels of low-density lipoproteins (“bad” cholesterol) and triglycerides in the blood and increases the level of high-density lipoproteins (“good” cholesterol) in the blood. This action helps to prevent and/or slow down the build-up of plaque in the arteries and veins.

Crestor is administered to reduce the risk of heart attack, stroke and other heart complications in patients with existing conditions such as diabetes, coronary heart disease, or other conditions.

For maximum therapeutic effect, the administration of Crestor should be accompanied with low fat diet and lifestyle changes such as exercising more, smoking less and losing weight.

CRESTOR Tablets for oral administration are formulations containing 5, 10, 20, or 40 mg of rosuvastatin.
Crestor should not be used by people who are less than 10years old.


Follow the instructions on your prescription sheet and always ask your doctor or pharmacist for clarification. The appropriate dose is determined by the doctor for each patient by taking a number of factors into consideration. Such factors include: the patient’s age, race, existing medical conditions, observed response to treatment and other drugs currently administered to the patient. As a patient, you should stick to the prescribed dose for as long as your doctor tells you to; do not stop taking Crestor or change your dose on your own without medical advice to that effect.

The usual initial or starting dose for adults is 5 mg to 10 mg daily while the maintenance dose can range from 5 mg to 40 mg as determined by your doctor. The medication should be taken once a day with or without food as directed.
For adults with Homozygous Familial Hypercholesterolemia, the recommended initial dose is 20 mg once daily while the maintenance dose is 20 mg to 40 mg once daily with or without food.
For Paediatric patients aged 10 to 17 years, the usual dose is 5 to 20mg daily, given with or without food. The maximum dose for paediatrics is 20 mg daily.

All doses are determined for each individual based on the goal of the treatment. It usually takes up to four weeks before the effects of Crestor are observed, therefore doses should be reviewed every four weeks or at the discretion of the doctor. However, it is very important that tests are performed after 40 days of Crestor administration in order to assess the response to treatment.


Crestor (Rosuvastatin) may worsen conditions such as liver diseases with prolonged use. Report any of the following symptoms to your doctor as soon as they are observed: Extreme fatigue, Darkened urine, Upper abdominal pain, loss of appetite, and jaundice or yellowing of the skin and eyes. These are very serious side effects and should not be ignored or left unattended to.
Some of the common side effects of Crestor may stop after a while, even without medical attention. Some of them include:
Body aches or joint pain
Congestion and runny nose
Dry or sore throat
Abdominal pain and nausea
Swallowing difficulties
Elevated sugar levels
Memory loss

If the body aches or muscle pains are accompanied by fever, you should contact your doctor immediately. Such aches and pains are likely signs of an uncommon problem with muscles that might lead to serious kidney problems. Patients who are 65 years or older and those that have kidney or thyroid problems are more prone to developing muscle problems.

Other possible side effects of Crestor include:
skin rash
unpleasant breath odour
vomiting of blood
bloated feeing
blurred vision
accidental injuries
Carious tooth
Chest pain
Tingling sensations at extremities
Difficulty with urination
Excess gas in stomach
Cardiac arrhythmias

Some drugs can have adverse reactions when taken with Crestor. For example, Antacids containing aluminium hydroxide and magnesium, and Bile acid sequestrants may lower Crestor levels in the blood stream. Therefore, they should be taken hours apart to avoid such adverse reactions.
Crestor and alcohol should not be taken together because it may lead to worsening of the side effects of the drug.


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