How does Flonase work?

Flonase

Fluticasone (flonase generic) energises the glucocorticoid receptors in humans that produce a powerful anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergic rhinitis (sternutation, Rhinorrhea, etc). It is used for the management of rhinal symptoms of seasonal and perennial non-allergic rhinitis in adults and children of 4 years of age and older.
The safety and effectiveness of Flonase Nasal Spray in children below 4 years of age have not been established.

Note

Use of excessive doses of corticosteroids may lead to signs or symptoms of Cushing’s syndrome and/or suppression of HPA function.
Contact your doctor immediately if you have been exposed to chickenpox or measles.
Use Flonase Nasal Spray at regular intervals for optimal effect. People from 12 years of age and above with seasonal hay-fever may find as-needed use of 200 mcg once daily effective for symptom control.
A decrease in nasal symptoms may occur as soon as 12 hours after starting therapy with Flonase Nasal Spray. Results indicate statistically major progress within the first day or two of treatment; however, the full benefit of Flonase Nasal Spray may not be reached until treatment has been administered for several days.
It is not known how Flonase react with foetus or breastfeeding children. Therefore, pregnant women and nursing mothers should consult with their doctor before using this medicine.
Due to the inhibitory effect of corticosteroids on wound healing, people who have experienced recent nasal septal ulcers, nasal surgery, or rhinal trauma should not use a nasal corticosteroid until healing has occurred.

Flonase Dosage

Fluticasone (generic flonase) propionate nasal spray is available as a 16 gm bottle, providing a total of 120 actuations. Each spray contains 50 mcg of fluticasone propionate. The correct amount of medication in each spray cannot be assured after 120 actuations even though the bottle is not completely empty. The bottle should be discarded when the labeled number of sprays has been used.
Adults: 2 sprays (50 mcg of fluticasone propionate each) per nostril daily. The total daily dose is 200 mcg (4 sprays). After the first few days, you may be able to reduce the dosage to 100 mcg (1 spray in each nostril) once daily for maintenance therapy.
Adolescents and Children 4 years of age and older: 1 spray (50 mcg) per nostril daily (100 mcg). This may be increased to 2 sprays (100 mcg) per nostril daily. The maximum dose should not exceed 200 mcg/day.

OVERDOSE

Chronic overdose may result in symptoms of hypercorticism. Therefore, seek medical help immediately overdose is suspected.

FLONASE SIDE EFECTS

Some side effects of flonase:
Giant hives
Skin rash
Edema of the face and tongue
Pruritus
Nettle rash
Bronchospasm
Asthma symptoms
Dyspnoea
Anaphylactic reactions
Loss of sense of taste and/or smell
Nasal septal perforation
Rhinal ulcer
Sore throat
Throat irritation and dryness
Cough
Hoarseness and voice changes.
Eye dryness and irritation
Conjunctivitis
Blurred vision
Glaucoma
Increased intraocular pressure
Cataracts.
Growth suppression

 

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