What is Nexium (Esomeprazole)?
Nexium generic name is esomeprazole, a drug employed to treat specific stomach and esophagus issues.
Nexium is qualified for treating gastroesophageal reflux dis-ease (GERD), as well as in conjunction with antibiotics for treating patients with H. pylori infection.
It is additionally accustomed to decrease the chance of gastric ulcers as well as in treating Zollinger-Ellison syndrome.
Nexium relieves trouble swallowing, and constant cough due to acid reflux.
In addition, it helps cure acid damage to the abdomen and esophagus, stops ulcers, and can assist in preventing cancer.
Nexium belongs to a category of medications called proton-pump inhibitors, which block the creation of acid in the gut.
Other proton-pump inhibitors include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), and pantoprazole (Protonix).
The Food and Drug Administration (FDA) accepted esomeprazole. Purchased the rights over the counter (OTC) edition of Nexium from Astra-Zeneca in 2012.
In 2014, the patent-expired, as well as a fresh Nexium OTC was released. AstraZeneca allegedly slashed a large number of occupations in the face of earnings as a result of expiration.
Nexium Side Effects
This side effects are connected with chance and severity:
Common negative effects of Nexium:
Feel Like Throwing Up
Infrequent negative effects of Nexium:
Sinus discomfort and Congestion
Incomplete or Infrequent Bowel Movements
Uncommon unwanted effects of Nexium:
Strange Liver Function Tests
Acquired Decrease of Cells in the Blood
Acute Disease of the Nose, Throat or Sinus
Severe Inflammation of the Pancreas
Clostridium Difficile Bacteria Associated Colitis
Reduced Blood Platelets
Lack of Granulocytes kind of White Blood Cell
High Blood Pressure
Disease because of the Candida Fungus
Redness of the Lining of the abdomen and Intestines
Stevens – Johnson syndrome
Toxic Epidermal Necrolysis
Yellowing of Skin or Eyes from Liver Problems
Difficulty in Swallowing
Breasts that are enlarged
Insufficient Vitamin B12
Redness of the Large Intestine
Low quantity of Magnesium
Energy that is low
Swelling of the Abdomen
Temporary Redness of Face and Neck
The over the counter (OTC) version of Nexium can be found in 20-milligram (mg) capsules.
Individuals shouldn’t utilize this medicine more than 2 weeks in a row, unless directed by their physician.
Nexium capsules with yellow stripes needs to be taken one hour before meals, consumed whole, and not chewed or crushed. Individuals with trouble swallowing can open capsule and mix.
Typical prescription power dosing is the following, even though your physician may prescribe various doses for you:
For grown-ups: 20 to 40 milligrams, once-daily for four to eight weeks
For kids (ages 1 to 1 1): 10 to 20 milligrams daily
For therapy of H. pylori: nexium 40 mg, once-daily along with amoxicillin (Amoxicot, Amoxil, Biomox) and clarithromycin (Biaxin), for 10 times.
Zollinger-Ellison syndrome: 40 milligrams, twice daily
Nexium Over dosage
One oral dose of esomeprazole at 510 mg/kg (about 103 times the human dose on a body surface-area basis), was fatal to rats. The important signals of severe toxicity were decreased motor activity, changes in frequency, tremor, ataxia, and occasional chronic convulsions.
The signs described in connection with willful NEXIUM overdose (small experience of doses over 240 milligrams/day) are passing. Single doses of 80 mg of esomeprazole were not eventful. Reports of over dosage with omeprazole in humans are often useful. Doses ranged up to 2,400 milligrams (120 times the usual recommended clinical dose). Symptoms were variable, but included confusion, somnolence, blurred vision, tachycardia, nausea, diaphoresis, flushing, headache, dry mouth, and other effects similar to those observed in in normal clinical experience (see omeprazole package insert – Adverse Side Effects). No specific antidote for esomeprazole is identified. Protein-bound, it’s not anticipated to be eliminated by dialysis. In case of over dosage, treatment should be supportive and symptomatic.
As with all the managing of any overdose, the likelihood of multiple-drug ingestion is highly recommended. For info on treatment of any drug-overdose contact a Poison Control center at 1 800 222 1222.
Missed Dose of Nexium
In the event you skip a dose, take it when you possibly can, however don’t “double up” to replace a missed dose.