What is Plavix (Clopidogrel)?


Plavix generic name is Clopidogrel bisulfate, an anti-platelet drug, in other words, a drug that inhibits the capability of platelets to clump together within a blood-clot. Clopidogrel prevents blood clots by binding to the P2Y12 receptor on platelets (ADP) from platelets. It belongs to a category of drugs. Drugs in this category contain ticagrelor (Brilinta) prasugrel and (Effient). Clopidogrel like ticlopidine (Ticlid) in chemical construction as well as in the way in which it works. Unlike ticlopidine, clopidogrel bisulfate doesn’t cause serious decreases of white cells and, thus, routine blood screening to find out in the event the white blood-cell count is not high isn’t essential during treatment. The chance of heart attacks and strokes (which typically are due to blood clots) is raised in patients having current history of stroke or heart-attack, and patients with peripheral vascular disorder. (Peripheral vascular disorder is just like atherosclerotic arterial disease or “hardening” of the arterial vessels where the arteries become narrowed. It appears in the legs and regularly causes claudication or pain). Clopidogrel bisulfate can be used to minimize the threat of strokes and heart attacks. Accepted by the US Food and Drug Administration in 1997.

Plavix Side Effects

The side effects are connected with clopidogrel by chance and severity:
Common negative side effects of plavix:
Head Pain
Joint Pain

Infrequent negative effects of clopidogrel:
Hemorrhage of the Stomach or Intestines

Uncommon unwanted effects of clopidogrel:
Strange Liver Function Tests
Abnormally reduced Blood Pressure
Acquired Decrease of Cells in the Blood
Acquired Hemophilia
Acute Liver Failure
Pustular Eruptions
Allergy resulting from Drug
Allergic Reaction causing Serum Sickness
Bleeding in the Respiratory Tract
Bleeding from Wound
Hemorrhage in the Abdomen
Urine that is bloody
Reduced Blood Platelets
Lack of Granulocytes kind of White Blood Cell
Discolored and Raisings of the Skin
Erythema Multiforme
Eye Hemorrhage
Giant Hives
Bleeding {in the Conjunctiva
Bleeding inside the Skull
Increased Eosinophils in the Blood
Redness of the Large Intestine
Redness of your skin with Blisters
Interstitial Pneumonitis
Kidney Disease
Allergic Reaction
Low Blood Counts due to bone-marrow Failure
Pneumonia high measure of Eosinophil White Blood Cells
Retinal Hemorrhage
Skin Rash
Stevens – Johnson syndrome
Stomach Ulcer
Thrombotic Thrombocytopenic Purpura
Toxic Epidermal Necrolysis
Ulcer of the Duodenum
Set of Blood within an Organ, Space or Tissue
Muscle Pain
Redness of Skin
Skin problem Defined by Bloated Itching Lesions
Flavor Issues

Plavix Dosage

A lot of folks take clopidogrel once a day.
It is wise consider this drug with food and plenty of water so as to cut back the negative effects.
Never quit taking clopidogrel without speaking to your own physician.
A lot of people who have angina or heart-attack start using a 300-mg one time a day, taken jointly with 75 to 325 milligrams of acetylsalicylic acid.

For those who current stroke, your physician will probably prescribe a dose of 75 milligrams daily.

Plavix Overdose

Platelet inhibition by clopidogrel can continue for the life span of the platelet. Overdose may lead to complications. One dose of clopidogrel or 2000 mg/kg was lethal to mice and to rats and kilogram to baboons. Apparent symptoms of severe toxicity were hard respiration, and gastrointestinal hemorrhage in creatures.
According to biological plausibility, clotting ability may be restored by platelet transfusion.
Never consider more clopidogrel than your physician has prescribed. In the event you’re worried that you just may have over-dosed, get to them immediately or telephone a poison control-center at (800) 222-1222.

Missed Dose

In the event you neglect to take your medicine, take it when you remember unless it is time for the next dose.
When it’s time for the next dose, miss the missed dose and continue to your typical dosing program. Do not take additional pills unless your physician advises you to do this.


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